RECOVERY FROM ALCOHOLIC INTOXICATION
Alcohol abuse is one of the main causes of liver disease. Alcoholic liver disease (ALD) has histopathological features: when exposed to a harmful irritant - alcohol, lipids accumulate in the liver, this condition called steatosis can be accompanied by episodes of inflammation (alcoholic hepatitis and steatohepatitis), leading to fibrosis and eventually to cirrhosis and liver cancer.

The strategy of using dietary fiber to develop new therapeutic approaches for the treatment of ALD conditions by modifying the composition and metabolites of the gut microbiome is attractive and relevant because its role in human health has been unequivocally identified and established.

A significant amount of research has focused on the role of gut microbiota content, microbial metabolism and gut barrier function in the susceptibility, development and outcome of these conditions. The liver is directly connected to the intestine through the portal system and bile and thus is constantly exposed to gut microorganisms and their metabolites. In turn, the liver can affect the composition of the gut microbiome through excreted bile acids. Therefore, if changes in the gut microbiome can cause ALD, modification of the composition and metabolites of the gut microbiome can be used to treat this condition.



By modulating the bacterial ecosystem of the intestine, pectin induces the production of a great variety of bacterial metabolites. Their physicochemical properties themselves modulate the absorption and release of specific nutrients in the intestine. Thus, the effect of pectin fiber varies along the entire gastrointestinal tract, affecting nutrient absorption in the small intestine and having a major impact on metabolic function/production in the colon. Thus, this dual effect of pectin is relevant for liver diseases such as ALS. In addition, pectin restores the enterohepatic cycle of bile acids (BA), after alcohol-induced dysregulation and leads to a decrease in plasma and hepatic BA levels. This is due to an increase in the number of enterobacteria that can process and metabolize the BA.

Graphic representation of the mechanisms involved in pectin-induced changes in alcoholic liver disease. Pectin polysaccharides are cleaved by "CAZymes" enzymes expressed by intestinal bacteria to make pectin work. Pectin increases hepatic bile acid synthesis by reducing "FXR" receptor activity and increasing levels of the "Cyp7a1" enzyme, which promotes the conversion of cholesterol to bile acids. The dotted line represents the pectin treatment process and the solid line represents the liver damage process.


THE SPECTIN DIETARY SUPPLEMENT OFFERS AN IDEAL SOLUTION FOR THE ELIMINATION OF HANGOVERS CAUSED BY TOXINS AND RECOVERY FROM ALCOHOL INTOXICATION.

TAKE SPECTIN FOR HANGOVER SYMPTOMS
Fatigue and weakness
Nausea
Headaches and muscle pain
Dizziness
Thirsty
Bad sleep
Irritability to light
Shivering
Decreased concentration
Mood disturbance and palpitations
It should be mentioned that taking common sorbents based on activated charcoal can have a traumatic effect on the mucous membrane. Especially the use of activated charcoal is not recommended for erosive and ulcerative lesions, hemorrhoidal bleeding.
Useful effects of sugar beet pectin when drinking alcohol is based on its sorption, that is complexing properties. SPECTIN dietary supplement is an enterosorbent, which, acting as a powerful absorbent, prevents the exit of intestinal metabolic products into the bloodstream, binds toxic compounds formed as a result of alcohol intoxication, and removes them from the body.
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